Scientific Publications

“Our stories always begin with clinical science, which is the driver for our technology.”

Roee Lazebnik, M.D., Ph.D. – Head, Medical Affairs & Clinical Development, NA

The North America Clinical Development and Medical Affairs organization has authored publications on a variety of therapeutic and diagnostic topics.

These publications are intended to inform and educate eye care practitioners about ophthalmic medical disease states and technologies.

Please see a list of publications below.

A New Approach to Internal Limiting Membrane Peeling: FINESSE® SHARKSKIN™ ILM Forceps

Mikhail Boukhny, Ph.D.*#; Alvin Relucio, M.D.**; Anna Katarzyna Talaga, Ph.D.**

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This white paper discusses internal limiting membrane peeling with the SHARKSKIN™ ILM Forceps.


*Alcon Research and Development, Fort Worth, TX;

**Alcon Medical Affairs, North America, Fort Worth, TX;

#No longer employed by Alcon Laboratories, Inc.

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An Overview of the Current Consensus, Clinical Impact and Management of Dry Eye

Priya Ramamoorthy, PhD, FAAO Alcon Medical Affairs, North America

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This paper discusses the etiology of dry eye, impact on clinical diagnosis and management and treatment options, including artificial tear solutions.
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Improved Refractive Outcomes in Femtosecond Laser Assisted Cataract Surgery (FLACS)

Elizabeth Yeu, MD*,** Albert Cheung, MD* Stephen Scoper, MD* Mohinder Merchea, OD, PhD, MBA***

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This white paper discusses how Femtosecond Laser Assisted Cataract Surgery (FLACS) improves clinical outcomes versus manual surgery.

*Virginia Eye Consultants, Norfolk, VA

**Assistant Professor of Ophthalmology, Eastern Virginia Medical School, Norfolk, VA

***Alcon Medical Affairs, North America, Ft. Worth, TX

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Importance of Rotational Stability and Tear Film Stability in Toric Contact Lens Wearers

Jessica Mathew, OD, PhD, FAAO Alcon Medical Affairs, North America

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This paper discusses the factors contributing to toric contact lens stability, including rotational stability and tear film stability.
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Etiology of Negative Dysphotopsia

Xiaolin Gu*, MD, PhD; Samuel Masket**, MD; Nicole Fram**, MD; George Pettit***, MD, PhD

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In a small number of cases, undesired visual disturbances may occur following an uneventful cataract surgery. These phenomena may take different forms, such as glare, halo, starburst, dark shadows, etc., and have been collectively named as “dysphotopsia.” This paper explores negative dysphotopsiae.


*Alcon North America Medical Affairs, Fort Worth, TX, USA
**Advanced Vision Care and the David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
***Alcon Vision Research, Fort Worth, TX, USA

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Topography-Guided Laser Assisted In-Situ Keratomileusis vs Small-Incision Lenticule Extraction Refractive Surgery: A Summary of Clinical Outcomes

Andrea Petznick, Diplom-AO (FH), PhD; Alcon Medical Affairs, North America

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This paper summarizes the clinical outcomes for topography-guided LASIK and Small-Incision Lenticule Extraction (SMILE) for refractive surgeries.
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Astigmatism Management with Toric IOLs – The Importance of Rotational Stability after IOL Implantation

Xiaolin Gu, MD, PhD, Alcon Medical Affairs, North America

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This paper discusses how preexisting corneal astigmatism is a key contributor to postoperative refractive error in patients undergoing cataract surgery. Toric IOLs can provide better-uncorrected distance visual acuity and greater spectacle independence for distance vision compared to non-toric IOLs. However, postoperative toric IOL rotation may occur, which results in unexpected postoperative astigmatism, and affects postoperative visual acuity, functional visual acuity, quality of vision, and patient satisfaction. A recent clinical study showed that the AcrySof® IQ toric IOL offers superior rotational stability compared with the Tecnis toric IOL.
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Contact Lens Technologies Created for Tear Film Stability and Comfort

Jessica Mathew, OD, PhD, FAAO, Alcon Medical Affairs, North America

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This white paper describes how the stability of the tear film is important for contact lens comfort. Contact lenses interfere with tear film stability and contribute to contact lens discomfort, which is a key reason for contact lens use discontinuation. The paper also outlines the technology behind DAILES TOTAL 1® contact lenses and how they support maintenance of tear film stability.
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Digitally Assisted Vitreoretinal Surgery: A new perspective

Alvin Relucio, MD, Alcon Medical Affairs, North America

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This white paper outlines the challenges associated with vitreoretinal surgery with an analogue microscope and discusses the advantages of Digitally Assisted Vitreoretinal Surgery (DAVS). DAVS provides several advantages over analogue microscopes during surgery, including improved images under high magnification, extended depth of field, no dependence on oculars, and options for digitally enhancing images.
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Femtosecond-Laser Assisted Cataract Surgery – A Clinical Perspective

Andrea Petznick, Diplom-AO (FH), PhD, Alcon Medical Affairs, North America

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This white paper discusses femtosecond-laser assisted cataract surgery with imaging guidance. Femtosecond laser cataract surgery is a modern technique that meets the technical and workflow needs for cataract surgery today; its integrated imaging capabilities enable the surgeon to visualize key anatomical landmarks to plan for a customized treatment with greater efficiency during surgery.
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